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云健康基因科技(上海)有限公司,是一家专注精准医学转化应用的基因组学高新技术企业,是中国精准医学高通量测序的领先者和倡导者之一,国家发改委首批基因检测示范中心,中国自贸区国际精准医疗合作中心,获批参加国家十三五精准医学大数据标准体系建设和基因大数据等国家级和上海市重大项目。

云健康建立了超高通量全基因组测序技术平台NovaSeq 6000、HiSeq X Ten、PacBio Sequel,并以基因检测医学检验所、基因大数据中心、创新研发中心、院士专家工作站、生命中心、高端诊所等生态链平台,提供从基因检测到精准健康精准医学全面解决方案,致力于倡导和引领预防医学,精准医疗事业,健康产业的发展,提升大众的健康生活品质,降低疾病风险。

云健康集团下设云健康基因工厂、云健康分子医学检验所、云健康基因大数据中心、云健康基因研究院、云健康生命中心、云健康高端诊所、云健康医生之家、云健康院士专家工作站。云健康拥有国家千人计划特聘专家领衔的国内外生命科学和生物信息专业技术团队近百人。建立了集基因检测、高端体检、健康咨询、健康调理、专家交流等服务于一体的综合大健康精准医疗服务平台。

目前,云健康已建立中国人群基因突变频率基准库,拥有中国人全基因组数据近2万例,测序通量名列全国前3位。未来,云健康将以基因技术为基点,在精准健康精准医学领域成为全球领先品牌。造福社会,造福民生。

云健康是一家行业内领先的专注为健康和临床研究提供全基因组检测和精准健康医疗解决方案的高科技企业,依托全球最先进的基因测序平台NovaSeq 6000、HiSeq X Ten、PacBio Sequel,正在为全世界的研究单位提供高效的全基因组测序服务,同时依托国际化的数据分析团队的支持,能够承接各类国内外研究项目。

 

同时云健康利用全基因组检测的结果,通过云健康生命中心,为有健康需求的广大消费者提供从基因检测到后续健康管理的全套服务。

 

云健康提供的服务是以全基因检测为核心的全面健康管理,传统的医疗理念还停留在患病就医的阶段,但是分子生物医学的快速发展将人们带入了一个新的时代-基因时代。通过全基因组测序检测,可以提前预知人们的疾病风险,并且制定个性化的干预方案,进行“治未病”的健康管理,降低患病风险或延缓疾病发生,享受健康生活。

 

云健康提供的是一站式的服务,基因检测只是一个环节,后期还提供非常多的健康管理服务,从基因检测到健康管理,对客户进行全方位的健康调理,达到“治未病”的目的。医院面对的是患病人群,不会关注“治未病”,也没有精力做健康管理。我们用云健康的平台来预防疾病,守护健康。

 

云健康出具的全基因组健康评估报告,是联合了多名美国基因分析专家、遗传咨询师等出具的国际评估报告。除了基因分析评估报告,我们还可以提供远程专家会诊咨询。

 

云健康作为基因科技与健康产业的跨界整合,打造创新健康体验新模式,努力成为健康领域的领军企业。而云健康一站式从全基因检测到治未病健康管理平台的开放,也预示着将会有越来越多的客户能够享受到云健康带来的高端健康服务,也必将为健康领域的产业模式和发展前景带来巨大影响。

大事记
2017
2016
2015
2014
2017.01

云健康发布全球首个针对健康人群的液态活检基因组测序检测产品

2017.04

南京云健康运营全球首批NovaSeq高通量测序平台

2017.05

云健康携手扬子集团与Harvard-MIT联合Broad研究所达成战略合作意向

2017.06

云健康在蒙古启动“一带一路”精准医学合作计划

2016.01

云健康医疗科技集团正式成立

2016.04

获批国家发改委第一批基因检测技术应用示范中心

2016.07

云健康与公利医院共推中国全民精准健康管理

2016.07

云健康长寿与健康研究所、基因健康研究所正式挂牌成立

2016.07

云健康参与由中国科学院北京基因组研究所牵头的《精准医学大数据处理和利用的标准化技术体系建设》项目

2016.09

云健康总裁(CEO)金刚博士荣获2016年上海市“白玉兰纪念奖”

2016.10

云健康成立并启动沪史上首个“健康教育协会健康传播分会”

2016.10

云健康关于“中国人群生命健康大数据建设项目”得到上海市经信委经费支持

2016.11

上海张江国家自主创新示范区批准云健康承担的“基于云健康生物数据库下的全基因组产品的试制应用项目”专项发展资金重点项目

2016.11

云健康获得近亿元战略投资,估值超过10亿元

2016.11

云健康院士专家工作站获上海市奉贤科学技术协会公布的“2016年度优秀院士专家工作站”之一

2016.11

云健康与上海国际医学中心正式签约合作

2015.01

云健康与Illumina召开全球发布会

2015.02

云健康门诊部成立

2015.04

云健康分子医学检验所成立

2015.05

云健康基因工厂正式启动&医学检验所挂牌&云健康院士工作站成立

2015.07

云健康HiSeq X Ten测序平台十台全产能规模化运营

2015.10

上海经信委超高通量测序平台建设项目获批

2015.12

成立中国自贸区国际精准医疗合作中心

2015.12

获得13项中华人民共和国国家版权局计算机软件著作权

2014.02

云健康成立

2014.09

云健康基因工厂成立

2014.10

云健康HiSeq X Ten实验室成立

发表文章
液态活检(6)

Malaria extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes. Mantel, PY, Hjelmqvist, D, Nilsson, S, Ravel, D, Ribeiro, M, Grüring, C, Ma, S, Padmanabhan, P, Trachtenberg, AJ, Ankarklev, J, Brancucci, N, Huttenhower, C, Duraisingh, MT, Ghiran, I, Kuo, WP, Martinelli, R, Marti, M., Nature Communications, 2016 a. 

Emerging technologies in extracellular vesicle-based molecular diagnostics. Jia S, Zocco D, Samuels ML, Chou MF, Chammas R, Skog J, Zarovni N, Momen-Heravi F, Kuo WP. Expert Rev Mol Diagn. 2014;14(3):307-21.

Short Course in Extracellular Vesicles – The Transition from Tissue to Liquid Biopsies. Lötvall J, Skog J, Vlassov AV, Sacido AA, Rohde E, Gere J, Kuo WP. Journal of Circulating Biomarkers. 2014, 3 (8), 1-5.

Detection Of Human c-Myc and EGFR Amplifications in Circulating Extracellular Vesicles in Mouse Tumour Models. Balaj L, Momen-Heravi F, Chen W, Sivaraman S, Zhang X, Ludwig N, Meese E, Wurdinger T, Noske D, Charest A, Hochberg FH, Vandertop P, Skog J, Kuo WP. Journal of Circulating Biomarkers. 2014, 3 (6), 1-7. 

Extracellular vesicles as shuttles of tumor biomarkers and anti-tumor drugs. Zocco D, Ferruzzi P, Cappello F, Kuo WP, Fais S. Front Oncol. 2014;4:267.

Current methods for the isolation of extracellular vesicles. Momen-Heravi F, Balaj L, Alian S, Mantel PY, Halleck AE, Trachtenberg AJ, Soria CE, Oquin S, Bonebreak CM, Saracoglu E, Skog J, Kuo WP. Biol Chem. 2013, 394(10):1253-62.

Alternative methods for characterization of extracellular vesicles. Momen-Heravi F, Balaj L, Alian S, Tigges J, Toxavidis V, Ericsson M, Distel RJ, Ivanov AR, Skog J, Kuo WP. Front Physiol. 2012;3:354. Impact of biofluid viscosity on size and sedimentation efficiency of the isolated microvesicles. Momen-Heravi F, Balaj L, Alian S, Trachtenberg AJ, Hochberg FH, Skog J, Kuo WP. Front Physiol. 2012;3:162.




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新一代测序(2)

Genomic landscape and genetic het¬erogeneity in gastric adenocarcinoma revealed by whole-genome sequencing. Swee Seong Wong, Kyoung-Mee Kim, Jason C. Ting, Kun Yu, Jake Fu Shawn Liu, Razvan Cristescu, Michael Nebozhyn, Lara Gong, Yong Gang Yue , Jian Wang , Chen Ronghua, Andrey Loboda, James Hardwick, Xiaoqiao Liu, Hongyue Dai, Jin JG, Xiang S. Ye , So Young Kang, In Gu Do, Joon Oh Park, Tae Sung Sohn, Christoph Reinhard , Jeeyun Lee, Sung Kim & Amit Aggarwal. Nature Communications, 2014. 5.

The draft genome of the large yellow croaker reveals well-developed innate immunity. Changwen Wu, Di Zhang, Mengyuan Kan, Zhengmin Lv, Aiyi Zhu, Yongquan Su, Daizhan Zhou, Jianshe Zhang , Zhou Zhang, Meiying Xu , Lihua Jiang, Baoying Guo, Ting Wang, Changfeng Chi , Yong Mao, Jiajian Zhou , Xinxiu Yu, Hailing Wang, Xiaoling Weng, Jin JG, Junyi Ye, Lin He & Yun Liu., Nature Communications, 2014. 5.

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生物信息分析(7)

AnyExpress: integrated toolkit for analysis of cross-platform gene expression data using a fast interval matching algorithm. Kim J, Patel K, Jung H, Kuo WP, Ohno-Machado L. BMC Bioinformatics. 2011;12:75.

Error margin analysis for feature gene extraction. Chow CK, Zhu HL, Lacy J, Kuo WP. BMC Bioinformatics. 2010; 11: 241.

Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates. Liu F, Jenssen TK, Trimarchi J, Punzo C, Cepko CL, Ohno-Machado L, Hovig E, Kuo WP. BMC Genomics. 2007;8:153.

Automatic correspondence of tags and genes (ACTG): a tool for the analysis of SAGE, MPSS and SBS data. Galante PA, Trimarchi J, Cepko CL, de Souza SJ, Ohno-Machado L, Kuo WP. Bioinformatics. 2007;23(7):903-5.

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. MAQC Consortium. Nat Biotechnol. 2006;24(9):1151-61. (Kuo WP is one of the key contributors)

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies. Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF 3rd, Freeman MW, Seed B, Jensen R, Church GM, Hovig E, Cepko CL, Park P, Ohno-Machado L, Jenssen TK. Nat Biotechnol. 2006;24(7):832-40.

Analysis of matched mRNA measurements from two different microarray technologies. Kuo WP, Jenssen TK, Butte AJ, Ohno-Machado L, Kohane IS. Bioinformatics. 2002;18(3):405-12.


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生物标志物(12)

Endothelial and circulating placental C19MC microRNAs distinguish propranolol-responsive infantile hemangioma from other vascular anomalies. Strub GM, Kirsh AL, Whipple MW, Kuo WP, Keller RB, Kapur RP, Perkins JA, Majesky MW. JCI Insight. 2016 Sep 8;1(14):e88856. doi: 10.1172/jci.insight.88856.

Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma. Hua Y, Choi PW, Trachtenberg AJ, Ng AC, Kuo WP, Ng SK, Dinulescu DM, Matzuk MM, Berkowitz RS, Ng SW., Oncotarget. 2016 Sep 1. doi: 10.18632/oncotarget.11808.

Molecular Changes in Endometriosis-Associated Ovarian Clear Cell Carcinoma. Worley, MJ, Liu, S, Hua, Y, Kwok, JS, Samuel, A, Hou, L, Shoni, M, Lu, S, Sandberg, EM, Keryan, A, Wu, D, Ng, SK, Kuo WP, Parra-Herran, CE, Tsui, SK, Welch, W, Crum, C, Berkowitz, RS and Ng, SW., Eur J Cancer. 2015 Jun 6. pii: S0959-8049(15)00442-6. doi: 10.1016/j.ejca.2015.05.011.

NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Tullius SG, Biefer HR, Li S, Trachtenberg AJ, Edtinger K, Quante M, Krenzien F, Uehara H, Yang X, Kissick HT, Kuo WP, Ghiran I, de la Fuente MA, Arredouani MS, Camacho V, Tigges JC, Toxavidis V, El Fatimy R, Smith BD, Vasudevan A, ElKhal A., Nat Commun. 2014 Oct 7;5:5101. doi: 10.1038/ncomms6101.

Genomewide Study of Salivary MicroRNAs for Detection of Oral Cancer. Momen-Heravi F, Trachtenberg AJ, Kuo WP, Cheng YS. J Dent Res. 2014 Apr 9;93(7 suppl):86S-93S.

miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway. Zhao JJ, Lin J, Zhu D, Wang X, Brooks D, Chen M, Chu ZB, Takada K, Ciccarelli B, Admin S, Tao J, Tai YT, Treon S, Pinkus G,Kuo WP, Hideshima T, Bouxsein M, Munshi N, Anderson K, Carrasco R. Cancer Res. 2014 Mar 15;74(6):1801-13. doi: 10.1158/0008-5472.CAN-13-3311-T. Epub 2014 Mar 5.

Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.Wang G, Lunardi A, Zhang J, Chen Z, Ala U, Webster KA, Tay Y, Gonzalez-Billalabeitia E, Egia A, Shaffer DR, Carver B, Liu XS, Taulli R,Kuo WP, Nardella C, Signoretti S, Cordon-Cardo C, Gerald WL, Pandolfi PP. Nat Genet. 2013 Jun 2. doi: 10.1038/ng.2654.

A microRNA panel to discriminate carcinomas from high-grade intraepithelial neoplasms in colonoscopy biopsy tissue. Wang S, Wang L, Bayaxi N, Li J, Verhaegh W, Janevski A, Varadan V, Ren Y, Merkle D, Meng X, Gao X, Wang H, Ren J, Kuo WP, Dimitrova N, Wu Y, Zhu H. Gut. 2013;62(2):280-9.

Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. Thompson AJ, Clark PJ, Singh A, Ge D, Fellay J, Zhu M, Zhu Q, Urban TJ, Patel K, Tillmann HL, Naggie S, Afdhal NH, Jacobson IM, Esteban R, Poordad F, Lawitz EJ, McCone J, Shiffman ML, Galler GW, King JW, Kwo PY, Shianna KV, Noviello S, Pedicone LD, Brass CA, Albrecht JK, Sulkowski MS, Goldstein DB, McHutchison JG, Muir AJ, Journal of Hepatology, 2012. 56(2): p. 313-319.

Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumor growth in mice. Xiang W, Ke Z, Zhang Y, Cheng GH, Irwan ID, Sulochana KN, Potturi P, Wang Z, Yang H, Wang J, Zhuo L, Kini RM, Ge R. J Cell Mol Med, 2009, Oct 29.

The first but not the second thrombospondin type 1 repeat of ADAMTS5 functions as an angiogenesis inhibitor. Sharghi-Namini S, Fan H, Sulochana KN, Potturi P, Xiang W, Chong YS,Wang Z, Yang H, Ge R, Biochem Biophys Res Commun. 2008. 371(2):215-9.

Angiogenic heterogeneity in head and neck squamous cell carcinoma: biological and therapeutic implications. Hasina R, Whipple ME, Martin LE, Kuo WP, Ohno-Machado L, Lingen MW. (2008) Lab Invest. Apr;88(4):342-53. Epub 2008 Feb 18.


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